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Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Related Experiment Video

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Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices
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Printable microfluidic systems using pressure sensitive adhesive material for biosensing devices.

Xin Wang1, David Nilsson, Petronella Norberg

  • 1Acreo AB, Box 787, SE-601 17, Norrköping, Sweden. xin.wang@acreo.se

Biochimica Et Biophysica Acta
|December 11, 2012
PubMed
Summary
This summary is machine-generated.

Printed microfluidic systems using pressure-sensitive adhesives offer a low-cost, rapid method for biosensor development. These systems enable viable point-of-care diagnostics on flexible substrates.

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Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
11:33

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Organic Electronics

Background:

  • Microfluidic systems are essential for guiding fluid analytes in biosensors.
  • Developing quick and economical microfluidic systems is key for point-of-care diagnostics.
  • Printing technology offers a low-cost approach for fabricating microfluidic devices on flexible substrates.

Purpose of the Study:

  • To present printed fluidic systems on flexible substrates using pressure-sensitive adhesive materials.
  • To evaluate the suitability of printable pressure-sensitive adhesives for microfluidic system fabrication.
  • To demonstrate the integration of printed microfluidics with biosensing devices.

Main Methods:

  • Printable pressure-sensitive adhesive materials (thermally dried and UV curable) were used to create microfluidic systems on flexible substrates.
  • A top sealing layer was laminated onto the printed microfluidic structures.
  • Flow tests were conducted using deionized water and water as a dielectric material.

Main Results:

  • Both thermally dried and UV curable adhesive materials proved suitable for capillary flow-driven fluidic devices.
  • Successful flow tests were performed with deionized water.
  • A printed electrolyte-gated organic field-effect transistor with an integrated microfluidic system demonstrated successful operation using water as the dielectric material.

Conclusions:

  • Printed microfluidic systems are advantageous due to their ease of processing and low cost.
  • This technology is expected to find increasing applications in the development of biosensing devices.
  • The findings contribute to the field of organic bioelectronics and its novel applications in biomedicine.