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Routine screening for Cushing's syndrome is not required in patients presenting with hirsutism
1Departments of Endocrinology, Erciyes University Medical School, 38039 Kayseri, Turkey. fktimur@erciyes.edu.tr
Context:
Prevalence of Cushing's syndrome (CS) in patients presenting with hirsutism is not well known.
Objective:
Screening of CS in patients with hirsutism.
Setting:
Referral hospital.
Patients And Other Participants:
This study was carried out on 105 patients who were admitted to the Endocrinology Department with the complaint of hirsutism.
Intervention:
All the patients were evaluated with low-dose dexamethasone suppression test (LDDST) for CS.
Main Outcome Measure:
Response to LDDST in patients presenting with hirsutism.
Results:
All the patients had suppressed cortisol levels following low-dose dexamethasone administration excluding CS. The etiology of hirsutism was polycystic ovary syndrome in 79%, idiopathic hirsutism in 13%, idiopathic hyperandrogenemia in 6%, and nonclassical congenital hyperplasia in 2% of the patients.
Conclusion:
Routine screening for CS in patients with a referral diagnosis of hirsutism is not required. For the time being, diagnostic tests for CS in hirsute patients should be limited to patients who have accompanying clinical stigmata of hypercortisolism.
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