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Updated: May 16, 2026

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Non-Hodgkin's Lymphomas, version 3.2012.

Andrew D Zelenetz1, William G Wierda, Jeremy S Abramson

  • 1Memorial Sloan-Kettering Cancer Center, USA.

Journal of the National Comprehensive Cancer Network : JNCCN
|December 11, 2012
PubMed
Summary

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Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
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This summary is machine-generated.

NCCN updates provide new treatment options for chronic lymphocytic leukemia and mantle cell lymphoma, along with revised surveillance imaging guidance for non-Hodgkin's lymphomas.

Area of Science:

  • Oncology
  • Hematology

Background:

  • The National Comprehensive Cancer Network (NCCN) periodically updates its Clinical Practice Guidelines for Oncology.
  • Non-Hodgkin's Lymphomas (NHL) encompass a diverse group of lymphoid malignancies requiring evolving treatment strategies.

Purpose of the Study:

  • To summarize key updates to the 2012 NCCN Guidelines for NHL.
  • To describe the clinical evidence supporting these guideline revisions.

Main Methods:

  • Review of recent NCCN Guidelines Insights focusing on NHL.
  • Analysis of clinical evidence supporting changes in treatment and surveillance recommendations.

Main Results:

  • Updated recommendations for chronic lymphocytic leukemia treatment, including options for elderly/frail patients and those with poor-risk cytogenetics.

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  • Revised guidance on surveillance imaging protocols for NHL follow-up.
  • Inclusion of new first-line consolidation options for mantle cell lymphoma.

    • Conclusions:

    • These NCCN Guidelines Insights reflect advancements in NHL management.
    • The updates aim to optimize treatment selection and follow-up care for patients with specific NHL subtypes.