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Femoral head allograft bone banking
1Department of Orthopaedic Surgery and Trauma, Royal Adelaide Hospital, South Australia.
The Australian and New Zealand Journal of Surgery
|April 1, 1990
Summary
Establishing a bone allograft program in South Australia improved bone safety for orthopedic procedures. Strict protocols minimized infection risks, demonstrating allografts
Area of Science:
- Orthopedic Surgery
- Tissue Banking
- Public Health
Background:
- Lack of uniform protocols for allograft bone collection, storage, and transfer in South Australia prior to 1986.
- High wastage rates observed due to infection or protocol non-adherence.
Purpose of the Study:
- To evaluate the safety and efficacy of a newly instituted allograft bone program.
- To assess the viability of using femoral heads for orthopedic procedures.
Main Methods:
- Collection of 100 femoral heads for allograft use.
- Utilization of 46 femoral heads in 31 patients for various orthopedic procedures.
- Implementation of strict criteria for donor bone acceptance and a diligent clerical service.
Main Results:
- No unsuspected hepatitis, syphilis, human immunodeficiency virus, or malignancy detected in the donor population.
- Zero infection cases reported in recipients.
- High wastage rate (46%) of collected femoral heads.
Conclusions:
- The donor population is a safe source for bone allografts.
- Strict adherence to protocols and donor selection criteria ensures allograft safety.
- Allograft bone can effectively address extensive bone deficiencies in orthopedic surgery.