Related Experiment Video
Updated: May 16, 2026

04:59
Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries
Published on: July 7, 2023
The posterior chamber phakic refractive lens (PRL): a review
R J Pérez-Cambrodí1, D P Piñero, T Ferrer-Blasco
1Department of Optics, Optometry Research Group, University of Valencia, Valencia, Spain.
Eye (London, England)
|December 11, 2012
Summary
Phakic refractive lens (PRL) implantation offers reversible vision correction with preserved accommodation. This review evaluates the limited published data on PRL outcomes and its long-term safety as a refractive surgery option.
Area of Science:
- Ophthalmology
- Refractive Surgery
Background:
- Phakic intraocular lenses (pIOLs) provide reversible vision correction, maintaining accommodation and minimizing higher-order aberrations.
- Potential risks of pIOLs include cataracts, uveitis, and endothelial cell loss.
- Currently, only two posterior chamber pIOL models are available: the implantable collammer lens and the phakic refractive lens (PRL).
Purpose of the Study:
- To review published literature on outcomes following phakic refractive lens (PRL) implantation.
- To provide an overview of PRL implantation results.
- To evaluate the potential of PRL as a refractive surgical option.
Main Methods:
- Literature review of published studies on PRL implantation outcomes.
- Analysis of existing data on safety and efficacy.
Main Results:
- Limited published reports exist for the phakic refractive lens (PRL).
- Some concerns regarding the long-term safety of PRL require further investigation.
- The review aims to consolidate current knowledge on PRL outcomes.
Conclusions:
- Phakic refractive lens (PRL) implantation is a refractive option with preserved accommodation.
- Further research is needed to fully understand the long-term safety and efficacy of PRL.
- The limited data necessitates cautious consideration of PRL as a refractive surgical choice.
Related Concept Videos
Focusing of Light in the Eye
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...

