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A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

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Nutrition and skin ulcers.

Milta O Little¹

¹Division of Geriatric Medicine, Department of Internal Medicine, Saint Louis University Medical Center, Saint Louis, Missouri 63104, USA. mlittle6@slu.edu

Current Opinion in Clinical Nutrition and Metabolic Care

|December 11, 2012

Summary

Optimizing nutrition is crucial for preventing and healing skin ulcers. While evidence is mixed, screening for malnutrition and monitoring nutrient intake are currently recommended best practices.

Area of Science:

Nutrition Science
Dermatology
Gerontology

Background:

Skin ulcerations are a significant cause of morbidity, mortality, and increased healthcare costs.
Risk factors include weight loss, protein-calorie malnutrition, and dehydration.
Effective interventions are needed to alleviate patient and healthcare system burdens.

Purpose of the Study:

To review current evidence on nutrition for preventing and managing skin ulcerations.
To highlight recent advances in nutritional interventions for wound healing.
To clarify the benefits and risks of nutritional supplementation.

Main Methods:

Review of nutritional status assessment markers.
Discussion of theoretical benefits of nutritional interventions on wound healing.

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Inclusion of recommendations for nutrient repletion.

Debate on risks and benefits of supplementation based on recent literature.

Main Results:

Evidence for most nutritional interventions is mixed, often due to poor study quality.
Common study limitations include variable designs, lack of control groups, small sample sizes, and short durations.
Nutritional status markers and their role in wound healing are discussed.

Conclusions:

Long-term randomized trials with clinically relevant endpoints are needed to confirm the benefits of individual nutrient supplementation.
Current best evidence emphasizes screening for malnutrition, calculating energy needs, and monitoring dietary nutrient intake.