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Pseudomembranes in rectal prolapse: a report of two cases

John D Coyne1

  • 1The Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK. johnnycoyne@doctors.org.uk

International Journal of Surgical Pathology
|December 11, 2012
PubMed

Insights

Pseudomembranes in colonic biopsies typically indicate antibiotic-related colitis. This study reports the novel finding of pseudomembranes in rectal prolapse cases, a previously undocumented association.

Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Pseudomembranes in colonic biopsies are a recognized indicator of antibiotic-related pseudomembranous colitis.
  • Rare instances of pseudomembranes in conditions other than C. difficile infection have been documented.

Observation:

  • This study observed the presence of pseudomembranes in colonic biopsies from patients presenting with rectal prolapse.
  • This association has not been previously reported in medical literature.

Findings:

  • The presence of pseudomembranes was noted in the context of rectal prolapse.
  • This finding expands the differential diagnosis for colonic pseudomembranes.

Implications:

  • The findings suggest that rectal prolapse may be an underrecognized condition associated with colonic pseudomembranes.
  • Further investigation is warranted to understand the mechanism and clinical significance of pseudomembranes in rectal prolapse.
Keywords:
mucosal prolapsepseudomembranespseudomembranous colitissolitary rectal ulcer

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