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Neural tube defects: a study in Puerto Rico
R Fernández1, C Colón, S A Fernández
1Section of Orthopaedics, University of Puerto Rico School of Medicine.
Boletin De La Asociacion Medica De Puerto Rico
|February 1, 1990
Summary
Neural tube defect incidence in Puerto Rico is high, contrary to global trends. This study found no decline in neural tube defect rates in Puerto Rico over nine years.
Area of Science:
- Public Health
- Pediatrics
- Epidemiology
Background:
- Global literature suggests a decline in neural tube defect (NTD) incidence.
- Understanding regional variations in NTD prevalence is crucial for targeted interventions.
Purpose of the Study:
- To determine the incidence and trends of neural tube defects in Puerto Rico over a nine-year period.
- To estimate the current prevalence of neural tube defects in Puerto Rico.
Main Methods:
- Revision of stillbirth certificates.
- Analysis of surgical reports for open neural tube defect closure procedures.
- Estimation of prevalence using death certificates and surgical reports.
Main Results:
- Puerto Rico exhibits a high incidence of neural tube defects, potentially the highest among US territories.
- The trend of neural tube defect incidence in Puerto Rico is not declining.
- Prevalence estimates were derived from multiple data sources.
Conclusions:
- Puerto Rico faces a significant burden of neural tube defects.
- Contrary to global observations, NTD rates are not decreasing in Puerto Rico.
- Continued surveillance and investigation into contributing factors are warranted.