Related Experiment Videos

Clinical characteristics of pediatric granular myringitis

Jessica R Levi1, Julie A Ames, Lyuba Gitman

  • 1Department of Otolaryngology Head and Neck Surgery, Boston University/Boston Medical Center, Boston, Massachusetts, USA.

Insights

Granular myringitis in children is a chronic ear condition often following ear tube placement or surgery. Treatments vary, with many cases showing intermittent or no long-term remission.

Area of Science:

  • Otolaryngology
  • Pediatric Medicine
  • Infectious Diseases

Background:

  • Granular myringitis is an uncommon inflammatory condition affecting the tympanic membrane.
  • It is characterized by the formation of granulation tissue on the eardrum.
  • Understanding its clinical presentation in children is crucial for effective management.

Purpose of the Study:

  • To delineate the clinical characteristics of pediatric patients diagnosed with granular myringitis.
  • To identify associated factors and previous treatments in children with this condition.

Main Methods:

  • A retrospective case series was conducted.
  • Chart review of 15 pediatric patients diagnosed with granular myringitis between 2006 and 2011.
  • Data collected included demographics, medical history, previous ear surgeries, treatments, and outcomes.

Main Results:

  • The average age of onset was 10 years, with a median symptom duration of 21 months.
  • Eighty-seven percent of patients had prior myringotomy tube placement, and 73% had a previous perforation.
  • Over half of the patients underwent myringoplasty or tympanoplasty before granular myringitis onset. Twenty-seven otolaryngologic procedures were performed on 14 patients.
  • Medical treatments included topical antibiotics and steroids, with some patients receiving oral antibiotics. Surgical interventions like laser resurfacing and curettage were performed.
  • Remission rates varied: 5 patients achieved long-term remission, 8 had intermittent remission, and 2 showed no remission.

Conclusions:

  • Granular myringitis in children is a chronic and often recalcitrant condition.
  • It is frequently preceded by procedures such as myringotomy tube insertion or myringoplasty/tympanoplasty.
  • Current medical and surgical interventions offer varied success, with many cases lacking permanent resolution.
Abstract

Related Concept Videos

Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.