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Rosacea: update on management and emerging therapies
Robyn S Fallen1, Melinda Gooderham
1McMaster University, Hamilton, ON, Canada.
Skin Therapy Letter
|December 11, 2012
Summary
Rosacea is an inflammatory skin condition impacting quality of life. Emerging therapies like topical ivermectin and oral doxycycline offer new hope for managing rosacea symptoms and improving patient well-being.
Area of Science:
- Dermatology
- Immunology
Background:
- Rosacea is a prevalent chronic inflammatory skin condition affecting self-esteem and quality of life.
- It is characterized by an altered innate immune response, leading to symptoms like papules, pustules, and erythema.
Purpose of the Study:
- To review current and emerging therapeutic strategies for rosacea management.
- To highlight the goals of rosacea therapy, focusing on symptom reduction and quality of life improvement.
Main Methods:
- Review of existing literature on rosacea treatments.
- Discussion of standard therapies (metronidazole, azelaic acid) and newer agents.
Main Results:
- Subantimicrobial dose oral doxycycline is approved for rosacea management in the US and Canada.
- Emerging therapies such as topical ivermectin, brimonidine, and oxymetazoline show promise.
Conclusions:
- Current and novel immunomodulatory therapies aim to restore cutaneous homeostasis in rosacea.
- These treatments offer improved management options for patients suffering from rosacea.
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