Related Experiment Video
Updated: May 16, 2026
Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
Pulse wave velocity, blood pressure and adipocytokines in young adults: the Rio de Janeiro study
Oswaldo Luiz Pizzi1, Andréa Araujo Brandão, Roberto Pozzan
1Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. olpizzi@cardiol.br
Insights
Pulse wave velocity (PWV) is linked to cardiovascular risk factors in young adults, particularly in males. PWV assessment can identify early vascular issues in this population.
Area of Science:
- Cardiovascular Physiology
- Vascular Health
- Metabolic Syndrome
Background:
- Limited data exists on noninvasive vascular assessment in young individuals.
- Understanding cardiovascular risk factors in youth is crucial for long-term health.
- Early identification of vascular impairment can prevent future cardiovascular events.
Purpose of the Study:
- To investigate the association between pulse wave velocity (PWV) and cardiovascular risk variables in young adults.
- To explore relationships with blood pressure, anthropometric, and metabolic factors, including adipocytokines.
- To determine the utility of PWV for early vascular health assessment in this demographic.
Main Methods:
- Assessed 96 adults (aged 26-35 years) for PWV using the Complior method.
- Measured blood pressure, BMI, glucose, lipid profile, leptin, insulin, adiponectin, and HOMA-IR.
- Stratified participants into PWV tertiles by gender for analysis.
Main Results:
- Higher PWV tertiles correlated with elevated blood pressure, BMI, insulin, HOMA-IR, and lower adiponectin.
- PWV showed significant positive correlations with blood pressure parameters, BMI, and LDL-cholesterol.
- Mean blood pressure and male gender were independently associated with PWV in regression analysis.
Conclusions:
- PWV is significantly associated with cardiovascular risk factors in young adults, especially males.
- Mean blood pressure is a key determinant of PWV in this age group.
- PWV measurement is a valuable tool for detecting vascular impairment in young individuals.
Background:
Data on noninvasive vascular assessment and their association with cardiovascular risk variables are scarce in young individuals.
Objective:
To evaluate the association between pulse wave velocity and blood pressure, anthropometric and metabolic variables, including adipocytokines, in young adults.
Methods:
A total of 96 individuals aged 26 to 35 years (mean 30.09 ± 1.92; 51 males) were assessed in the Rio de Janeiro study. Pulse wave velocity (Complior method), blood pressure, body mass index, glucose, lipid profile, leptin, insulin, adiponectin and insulin resistance index (HOMA-IR) were analyzed. Subjects were stratified into three groups according to the PWV tertile for each gender.
Results:
The group with the highest pulse wave velocity (PWV) tertile showed higher mean systolic and diastolic blood pressure, mean blood pressure, body mass index, insulin, and HOMA-IR, as well as lower mean adiponectin; higher prevalence of diabetes mellitus/glucose intolerance and hyperinsulinemia. There was a significant positive correlation of PWV with systolic blood pressure, diastolic blood pressure, pulse pressure and mean blood pressure, body mass index, and LDL-cholesterol, and a negative correlation with HDL-cholesterol and adiponectin. In the multiple regression model, after adjustment of HDL-cholesterol, LDL-cholesterol and adiponectin for gender, age, body mass index and mean blood pressure, only the male gender and mean blood pressure remained significantly correlated with PWV.
Conclusion:
PWV in young adults showed a significant association with cardiovascular risk variables, especially in the male gender, and mean blood pressure as important determinant variables. The findings suggest that PWV measurement can be useful for the identification of vascular impairment in this age group.
More Related Videos
Related Concept Videos
01:28Factors affecting Blood pressure
Physiological Factors:
01:19Assessing Blood pressure using a doppler ultrasound
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
01:19Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
01:17Measurement of Blood Pressure
01:17Hormonal Regulation of Blood Pressure
Epinephrine and Norepinephrine
The adrenal medulla releases epinephrine and norepinephrine, catecholamines that enhance and extend the sympathetic or "fight or flight" physiological response. These hormones escalate heart rate and the force of contraction while...
01:15Assessment of blood pressure in brachial artery(one-step method)
Prepare for the Procedure: