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Related Concept Videos

Overview of Cell Signaling01:23

Overview of Cell Signaling

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
Overview of Cell Signaling01:23

Overview of Cell Signaling

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
Types of Signaling Molecules01:32

Types of Signaling Molecules

In multicellular organisms, many molecules transmit signals between cells to pass information. These signals vary in complexity and include small peptides, nucleotides, steroids, fatty acid derivatives, and dissolved gases such as nitric oxide. Some signaling molecules diffuse through the plasma membrane to act locally between neighboring cells or travel long distances. Others remain attached to the cell surface, transmitting information to other cells only when they make contact. In some...
Types of Signaling Molecules01:32

Types of Signaling Molecules

In multicellular organisms, many molecules transmit signals between cells to pass information. These signals vary in complexity and include small peptides, nucleotides, steroids, fatty acid derivatives, and dissolved gases such as nitric oxide. Some signaling molecules diffuse through the plasma membrane to act locally between neighboring cells or travel long distances. Others remain attached to the cell surface, transmitting information to other cells only when they make contact. In some...
What is Cell Signaling?02:03

What is Cell Signaling?

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
What is Cell Signaling?02:03

What is Cell Signaling?

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.

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Related Experiment Video

Updated: May 16, 2026

A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro
09:50

A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro

Published on: August 27, 2015

Mechanical cues in cellular signalling and communication.

Nickolay V Bukoreshtliev1, Kristina Haase, Andrew E Pelling

  • 1Department of Physics, University of Ottawa, Ottawa, ON, Canada.

Cell and Tissue Research
|December 11, 2012
PubMed
Summary

Multicellular organisms use cell mechanics to sense their environment. This review explores how mechanical cues influence cell communication and function within the body.

Area of Science:

  • Cellular biology
  • Biophysics
  • Physiology

Background:

  • Multicellular organisms consist of cells within a complex microenvironment.
  • Cells communicate to perform specialized functions.
  • Cells are physical entities responding to mechanical cues from their surroundings.

Purpose of the Study:

  • To review current understanding of cell mechanics.
  • To highlight the role of mechanical cues in cell function.
  • To demonstrate the interplay between mechanical cues and cell communication.

Main Methods:

  • Literature review of cell mechanics research.
  • Analysis of studies on cellular responses to mechanical stimuli.
  • Examination of cell-cell communication pathways influenced by mechanical factors.

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Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence
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Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence

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Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells
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Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells

Published on: July 16, 2013

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Last Updated: May 16, 2026

A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro
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A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro

Published on: August 27, 2015

Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence
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Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence

Published on: March 5, 2022

Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells
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Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells

Published on: July 16, 2013

Main Results:

  • Cells possess mechanisms to sense microenvironmental physical properties and forces.
  • Mechanical cues significantly impact cellular responses in vivo.
  • Emerging evidence shows a connection between mechanical cues and cell communication.

Conclusions:

  • Cell mechanics is crucial for understanding cellular behavior.
  • Mechanical forces are integral to cell-cell communication.
  • Further research into mechanobiology can reveal new physiological insights.