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Updated: May 16, 2026

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
Published on: August 17, 2022
Progressive breathlessness in an Afro Caribbean hypertensive subject
Girish Dwivedi1, Robert J MacFadyen, Chetan Varma
1University of Birmingham, Birmingham, UK. g.dwivedi@bham.ac.uk
Echocardiography has limitations in assessing heart structure in Black hypertensive patients with heart failure. Cardiovascular magnetic resonance (CMR) offers superior tissue characterization for diagnosing conditions like hypertrophic cardiomyopathy.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Echocardiography's limitations in structural assessment for Black hypertensive patients with heart failure.
- Cardiovascular magnetic resonance (CMR) offers advanced myocardial tissue characterization for noninvasive diagnosis.
Observation:
- An illustrative case of hypertrophic cardiomyopathy in a British Afro-Caribbean hypertensive patient.
- Screening echocardiography revealed features suggestive of familial amyloidosis.
Findings:
- CMR examination confirmed its utility in differentiating cardiac pathologies.
- The case highlighted variations in hypertrophic cardiomyopathy presentation.
Implications:
- CMR is crucial for accurate diagnosis when echocardiography is incomplete.
- Recognizing atypical presentations of hypertrophic cardiomyopathy is vital for correct diagnosis.
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