Adenosine-induced atrial fibrillation during fractional flow reserve measurement

We present the case of a 44 year-old man referred for coronary angiography with a history of coronary artery disease. Following administration of intra-coronary adenosine for fractional flow reserve (FFR) assessment, the patient developed atrial fibrillation (AF). While well described during non-invasive stress testing, this is the first description in the literature of AF following adenosine administration for FFR. The growing usage of FFR during diagnostic coronary angiography makes this an important side effect to consider. Our subsequent management and follow-up is presented.