Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thermographic assessment of patch-test responses.

A J Baillie1, P A Biagioni, A Forsyth

  • 1Department of Pharmacy, University of Strathclyde, Glasgow, U.K.

The British Journal of Dermatology
|March 1, 1990
PubMed
Summary

Infrared thermography can distinguish between allergic and irritant skin reactions. This non-invasive method quantifies allergic responses, showing higher temperatures at allergic patch test sites.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychedelic-assisted therapy as a complex intervention: implications for clinical trial design.

Therapeutic advances in psychopharmacology·2025
Same author

An analysis of referral patterns of traumatic brain injury at Groote Schuur Hospital Trauma Centre.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2024
Same author

Damage control laparotomy outcomes in a major urban trauma centre.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2022
Same author

Planning slow Mohs excision margins for lentigo maligna: a retrospective nonrandomized cohort study comparing reflectance confocal microscopy margin mapping vs. visual inspection with dermoscopy.

The British journal of dermatology·2020
Same author

A contemporary prospective review of 205 consecutive patients with penetrating colon injuries.

Injury·2020
Same author

How does muscularity assessed by bedside methods compare to computed tomography muscle area at intensive care unit admission? A pilot prospective cross-sectional study.

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2020

Area of Science:

  • Dermatology
  • Allergy and immunology
  • Medical imaging

Background:

  • Patch testing is crucial for diagnosing contact allergies.
  • Differentiating allergic from irritant reactions can be challenging.
  • Objective quantification of patch test responses is needed.

Purpose of the Study:

  • To evaluate infrared thermography for quantifying allergic and irritant patch test responses.
  • To assess the correlation between thermographic parameters and clinical assessments of allergic reactions.
  • To compare thermographic responses to different allergen formulations.

Main Methods:

  • Infrared thermography was used to measure temperature changes at patch test sites in volunteers and patients.
  • Allergic responses to nickel sulfate and irritant responses to sodium lauryl sulfate were studied.

Related Experiment Videos

  • Thermographic data were compared with clinical evaluations and different allergen preparations.

    • Main Results:

    • Allergic reaction sites showed increased temperatures ('hot areas') compared to normal skin.
    • Thermographic parameters (temperature, area) correlated well with clinical severity of allergic reactions.
    • Irritant reaction sites did not exhibit elevated temperatures.
    • Allergen formulations affected the thermographic response, with aqueous solutions eliciting stronger reactions than those in soft paraffin.

    Conclusions:

    • Infrared thermography is a non-invasive technique capable of differentiating between allergic and irritant patch test reactions.
    • The technique can objectively quantify the severity of allergic contact dermatitis.
    • Thermography offers a valuable tool for assessing patch test outcomes and allergen formulation effects.