Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Irritable Bowel Syndrome01:23

Irritable Bowel Syndrome

DefinitionIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent combinations of abdominal pain, bloating, diarrhea, or constipation.Pathophysiology of irritable bowel syndromeIts pathophysiology is multifactorial, involving disturbances in motility, sensory processing, microbial balance, barrier integrity, and gut–brain communication. These mechanisms interact to produce symptoms that vary across IBS subtypes.Altered Motility PatternsDisordered...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Accelerated brain aging in methamphetamine use disorder revealed by functional connectivity.

National science review·2026
Same author

The Phase-Amplitude Coupling Induced by Drug Cues in Individuals With Methamphetamine Use Disorder During Withdrawal.

Brain and behavior·2026
Same author

Sleep Slow-Wave and Spindle Alterations in Young Smokers Correlated With the Severity of Cigarette Exposure.

Addiction biology·2026
Same author

Risk classification of internet gaming disorder based on neurobiological subtyping from impulsivity-linked resting-state functional connectivity: a longitudinal design study.

BMC medicine·2026
Same author

Altered Topological Properties of White-Matter Functional Networks in Young Smokers.

Addiction biology·2026
Same author

Hippocampal transcranial temporal interference stimulation reduced craving in methamphetamine use disorder.

Addictive behaviors·2025

Related Experiment Video

Updated: May 16, 2026

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS
07:56

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS

Published on: June 24, 2025

Increased interhemispheric resting-state functional connectivity in functional dyspepsia: a pilot study.

Guangyu Zhou1, Peng Liu, Fang Zeng

  • 1Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi'an, Shaanxi, China.

NMR in Biomedicine
|December 11, 2012
PubMed
Summary

Patients with functional dyspepsia (FD) show altered brain connectivity. This study found higher global interhemispheric resting-state functional connectivity (RSFC) in FD patients compared to controls, indicating brain communication differences.

Keywords:
functional MRIfunctional connectivityfunctional dyspepsiainterhemispheric

More Related Videos

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
07:13

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Published on: May 27, 2020

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
08:33

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

Published on: January 5, 2024

Related Experiment Videos

Last Updated: May 16, 2026

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS
07:56

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS

Published on: June 24, 2025

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
07:13

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Published on: May 27, 2020

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
08:33

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

Published on: January 5, 2024

Area of Science:

  • Neuroimaging
  • Gastroenterology
  • Psychiatry

Background:

  • Functional dyspepsia (FD) is linked to regional brain activity abnormalities.
  • Interhemispheric functional connectivity changes in FD are not well understood.

Purpose of the Study:

  • To investigate alterations in interhemispheric resting-state functional connectivity (RSFC) in patients with FD.
  • To compare brain connectivity patterns between FD patients and healthy controls.

Main Methods:

  • Resting-state functional MRI (fMRI) was used in 26 FD patients and 20 healthy controls.
  • Interhemispheric RSFC was mapped using Pearson correlation of homotopic voxel time series.
  • Statistical analyses included independent t-tests and permutation-based nonparametric tests with TFCE correction.

Main Results:

  • FD patients exhibited significantly higher global interhemispheric RSFC than healthy controls (p < 0.01).
  • Voxelwise analysis revealed increased interhemispheric RSFC in the anterior cingulate cortex, insula, and thalamus in FD patients (p < 0.01).

Conclusions:

  • This study provides preliminary evidence of abnormal interhemispheric functional connectivity in FD.
  • Findings contribute to understanding the pathophysiology of functional dyspepsia.