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Published on: September 20, 2016

RagD gene expression and NRF2 mutations in lung squamous cell carcinomas.

Hidefumi Sasaki1, Masayuki Shitara, Keisuke Yokota

  • 1Department of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi 467-8601, Japan.

Oncology Letters
|December 11, 2012
PubMed
Summary

RagD, an activator of the mTOR pathway, is linked to lung cancer cell proliferation. Higher RagD expression correlates with NRF2 mutations and advanced tumor stages in lung squamous cell carcinoma.

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