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Updated: May 16, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
Acute kidney injury after cardiovascular surgery: an overview
Juan Jose Olivero1, Juan Jorge Olivero, Peter Tuan Nguyen
1Methodist DeBakey Heart & Vascular Center, The Methodist Hospital, Houston, TX, USA.
Abstract:
Acute kidney injury is a complication of open-heart surgery that carries a poor prognosis. Studies have shown that postoperative renal function deterioration in cardiovascular surgery patients increases in-hospital mortality and adversely affects long-term survival. Identifying individuals at risk for developing AKI and aggressive early intervention is extremely important to optimize outcomes. This paper provides an overview of the etiology, prognostic markers, risk factors, and prevention of AKI and treatments that may favorably affect outcomes.
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