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Related Concept Videos

Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
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Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs

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Antidepressant Drugs: Overview01:25

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Disorders of the Male Reproductive System01:20

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Related Experiment Video

Updated: May 16, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

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Published on: May 30, 2025

[Sexual dysfunction induced by antidepressants and antipsychotics].

O G Licitsyna, M Ansseau, P Gernay

    Terapevticheskii Arkhiv
    |December 11, 2012
    PubMed
    Summary

    Newer antidepressants and antipsychotics can cause sexual dysfunction, impacting patient quality of life and treatment adherence. This review examines these side effects and suggests management strategies.

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    Area of Science:

    • Psychopharmacology
    • Sexual Medicine

    Context:

    • Growing use of novel antidepressants (AD) and antipsychotics (AP) for various mental health conditions.
    • Increased clinical interest in psychotropic drug-induced sexual dysfunction.
    • Limited scientific data and underestimation of this adverse effect by specialists.

    Purpose:

    • To review the impact of AP and AD on sexual function.
    • To compare sexual side effects across different drug classes.
    • To propose management strategies for psychotropic-induced sexual dysfunction.

    Summary:

    • Psychotropic medications, including new-generation antidepressants and antipsychotics, are associated with sexual dysfunction.
    • This dysfunction negatively affects patient quality of life and treatment adherence, potentially leading to mental illness recurrence.
    • The prevalence and nature of these sexual side effects are not well-documented and often overlooked in clinical practice.

    Impact:

    • Highlights the underrecognized issue of sexual dysfunction caused by psychotropic medications.
    • Provides a comparative overview of drug-induced sexual side effects.
    • Offers potential strategies to mitigate these adverse effects, improving patient outcomes and treatment adherence.