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A new anthraquinone glycoside from the root of Rheum officinale Baill
Zheng-Xiang Xia1, Zhong-Yan Tang, Rui An
1School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Abstract:
A new and a known anthraquinone glycosides were isolated from the ethanol extract of the roots of Rheum officinale Baill. The extract was purified by various chromatographies, such as silica gel, Sephadex LH-20, RP-C18 column chromatography and HPLC. Two compounds were identified by the spectroscopic techniques of NMR, MS, and chemical method. In addition, they were tested for their cytotoxic effects against HepG2 cell. Unfortunately, they showed no or weak activity.