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Related Concept Videos

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Functional Classification of Joints01:09

Functional Classification of Joints

Functional Classification of Joints
The functional classification of joints is determined by the amount of mobility between the adjacent bones. Joints are functionally classified as a synarthrosis or immobile joint, an amphiarthrosis or slightly moveable joint, or as a diarthrosis, a freely moveable joint. Fibrous and cartilaginous joints can be functionally classified as either synarthroses  or amphiarthroses, whereas all synovial joints are classified as diarthroses.
Synarthrosis
An immobile...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...

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Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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[Classification criteria for rheumatoid arthritis].

Gaël Mouterde1, Jacques Morel

  • 1CHU de Montpellier, hôpital Lapeyronie, département de rhumatologie, Université Montpellier-1, UMR 5535, 34295 Montpellier Cedex 5, France. g-mouterde@chu-montpellier.fr

La Revue Du Praticien
|December 12, 2012
PubMed
Summary

The 2010 ACR/EULAR criteria improve early rheumatoid arthritis (RA) diagnosis by assessing joint involvement, serology, acute-phase response, and symptom duration. This aids in identifying patients needing early treatment for persistent or erosive disease.

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Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography

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Last Updated: May 16, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
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Area of Science:

  • Rheumatology
  • Clinical Immunology

Context:

  • The 1987 American College of Rheumatology (ACR) criteria were designed to differentiate rheumatoid arthritis (RA) from other rheumatic conditions, not for early RA diagnosis.
  • Identifying early arthritis patients who will develop persistent or erosive disease is crucial for timely treatment with disease-modifying antirheumatic drugs (DMARDs).

Purpose:

  • To outline the development and components of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis.
  • To establish a gold standard for classifying early RA, utilizing methotrexate treatment as a benchmark.

Summary:

  • The 2010 ACR/EULAR criteria require synovitis in at least one joint and the absence of an alternative diagnosis.
  • Classification involves a total score of 6 or more out of 10, derived from four domains: joint involvement, serology, acute-phase response, and symptom duration.
  • These criteria aim to accurately identify patients with definite RA, facilitating earlier intervention.

Impact:

  • Facilitates earlier and more accurate diagnosis of rheumatoid arthritis.
  • Enables timely initiation of DMARDs for patients at risk of severe disease progression.
  • Improves patient outcomes by allowing for prompt and appropriate management of early RA.