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Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
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Comparative effectiveness research in the United States: a progress report.

Sean D Sullivan1, Josh J Carlson, Ryan N Hansen

  • 1Pharmaceutical Outcomes Research and Policy Program, School of Pharmacy, University of Washington, 1959 NE Pacific Ave, Seattle, WA 98195-7630, USA. sdsull@uw.edu

Journal of Medical Economics
|December 12, 2012
PubMed
Summary

The United States is advancing comparative effectiveness research (CER) to enhance healthcare efficiency and decision-making for patients and providers. This paper reviews CER

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Area of Science:

  • Health Services Research
  • Health Economics
  • Evidence-Based Medicine

Background:

  • The US healthcare system faces challenges in efficiency despite significant resource allocation.
  • Comparative Effectiveness Research (CER) has emerged as a key strategy to address these challenges.
  • High expectations and substantial investments are driving the CER agenda in the United States.

Purpose of the Study:

  • To discuss the evolution of comparative effectiveness research (CER) in the United States.
  • To provide a progress report on CER initiatives.
  • To identify and analyze the challenges faced by CER in the US.

Main Methods:

  • Literature review of CER evolution and progress.
  • Analysis of public and private investments in CER.
  • Discussion of reported challenges in CER conduct and reporting.

Main Results:

  • CER is a growing field in the US, supported by significant public and private funding.
  • CER aims to improve healthcare efficiency and inform decision-making for various stakeholders.
  • Progress has been made, but challenges remain in the conduct and reporting of CER.

Conclusions:

  • Comparative Effectiveness Research (CER) is a critical initiative for improving US healthcare.
  • Continued investment and strategic planning are necessary to overcome CER challenges.
  • Successful implementation of CER is expected to lead to better healthcare decisions and outcomes.