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Updated: May 16, 2026

Assessing the Effects of Music Listening on Psychobiological Stress in Daily Life
Published on: February 2, 2017
Does music influence stress in mechanically ventilated patients?
Linda L Chlan1, William C Engeland, Kay Savik
1School of Nursing, University of Minnesota, 5-160 Weaver-Densford Hall, 308 Harvard St. SE, Minneapolis, MN 55455, United States. chlan001@umn.edu
Music did not significantly reduce stress biomarkers in mechanically ventilated patients. While some trends suggested potential benefits, further research is needed to confirm if patient-directed music listening impacts stress levels during ventilatory support.
Area of Science:
- Critical Care Medicine
- Psychoneuroimmunology
- Health Psychology
Background:
- Mechanically ventilated patients experience significant physiological and psychological stress.
- Effective, non-pharmacological interventions are needed to mitigate stress in the intensive care unit (ICU) setting.
- Music listening is a potential low-risk intervention for stress reduction.
Purpose of the Study:
- To investigate the effect of patient-directed music on stress levels in mechanically ventilated patients.
- To compare music intervention with noise-canceling headphones and usual care.
Main Methods:
- A randomized controlled trial was conducted across 12 Midwestern US ICUs.
- Patients receiving ventilatory support were assigned to patient-directed music, headphones only, or usual care.
- Twenty-four hour urinary free cortisol (UFC) levels were measured as a primary biomarker of stress.
Main Results:
- Analysis controlling for illness severity, gender, and baseline UFC showed no significant differences in UFC levels among the three groups.
- No statistically significant reduction in urinary free cortisol was observed with patient-directed music intervention.
Conclusions:
- Patient-directed music did not significantly reduce urinary free cortisol levels in mechanically ventilated patients.
- Although not statistically significant, a trend towards less profound UFC spikes was noted in the music group.
- Further investigation is required to determine the potential, albeit unproven, stress-mitigating effects of music in this population.
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