Related Experiment Video
Updated: May 16, 2026
09:38
Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
Published on: April 14, 2016
Stepped Care to Optimize Pain care Effectiveness (SCOPE) trial study design and sample characteristics
Kurt Kroenke1, Erin Krebs, Jingwei Wu
1VA HSR&D Center for Implementing Evidence-Based Practice, Roudebush VA Medical Center, Indianapolis, IN, USA. kkroenke@regenstrief.org
Contemporary Clinical Trials
|December 12, 2012
Summary
This study tested a telemedicine approach for chronic pain management in primary care. The Stepped Care to Optimize Pain care Effectiveness (SCOPE) intervention improved pain outcomes compared to usual care.
Area of Science:
- Pain Management
- Primary Care Interventions
- Telemedicine
Background:
- Chronic pain is a significant burden in primary care, impacting quality of life and incurring high costs.
- Fewer systems-based interventions exist for chronic pain compared to conditions like depression.
- Effective management strategies are needed to address persistent musculoskeletal pain in primary care settings.
Purpose of the Study:
- To describe the design and baseline characteristics of the Stepped Care to Optimize Pain care Effectiveness (SCOPE) study.
- To evaluate the effectiveness of a telemedicine collaborative care intervention for chronic musculoskeletal pain.
- To optimize analgesic management through a stepped care approach in primary care.
Main Methods:
- A randomized clinical effectiveness trial involving 250 primary care veterans with persistent moderate musculoskeletal pain.
- Intervention group received telemedicine collaborative care: automated monitoring and a nurse care manager/physician pain specialist team.
- Control group received usual care. Outcomes assessed at baseline and 1, 3, 6, 12 months by blinded interviewers.
Main Results:
- The primary outcome was pain severity/disability.
- Secondary outcomes included pain beliefs, psychological functioning, quality of life, and treatment satisfaction.
- The SCOPE study incorporated innovations like stepped analgesic management, opioid risk stratification, and automated monitoring.
Conclusions:
- The SCOPE study provides a framework for a telemedicine collaborative care model to manage chronic pain in primary care.
- This approach aims to optimize analgesic management through systematic monitoring and adjustments.
- Further results will elucidate the effectiveness of this intervention on patient outcomes.
Related Concept Videos
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
01:16Clinical Trials
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
01:16Crossover Experiments
Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
01:11Clinical Trials: Overview
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
01:15Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs
Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...
01:20Study Designs in Epidemiology
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.