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Updated: Jul 20, 2026

Mouse Model of Surgically-induced Endometriosis by Auto-transplantation of Uterine Tissue
Published on: January 6, 2012
MRI findings of sciatic endometriosis
P Moeser1, P D Donofrio, N Karstaedt
1Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27103.
Endometriosis can rarely cause sciatic mononeuropathy, leading to leg pain and weakness. Magnetic resonance imaging (MRI) helped diagnose this condition by visualizing endometriotic tissue near the sciatic nerve.
Area of Science:
- Neurology
- Gynecology
- Radiology
Background:
- Endometriosis is a condition where uterine-like tissue grows outside the uterus.
- Sciatic mononeuropathy, or dysfunction of the sciatic nerve, can have various causes.
- This case explores a rare presentation of endometriosis impacting the sciatic nerve.
Observation:
- A woman presented with cyclical hip pain related to menstruation.
- Symptoms included right leg weakness and sensory loss, indicative of sciatic nerve involvement.
- Physical and electrodiagnostic examinations supported sciatic nerve dysfunction.
Findings:
- Magnetic resonance imaging (MRI) revealed abnormal signals near the right sciatic nerve.
- These signals were consistent with endometriotic tissue.
- The abnormal signals showed partial regression following endometriosis treatment.
Implications:
- This case highlights endometriosis as a rare cause of sciatic mononeuropathy.
- It demonstrates the diagnostic value of MRI in identifying pelvic disorders.
- Early diagnosis and treatment can potentially alleviate neurological symptoms associated with endometriosis.
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