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Updated: May 16, 2026
Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
Published on: March 24, 2022
Development of multi-planar dose verification by use of a flat panel EPID for intensity-modulated radiation therapy
Yuji Nakaguchi1, Fujio Araki, Tomohiro Kouno
1Department of Radiological Technology, Kumamoto University Hospital, 1-1-1 Honjyo, Kumamoto, Japan. nakaguchi@fc.kuh.kumamoto-u.ac.jp
Abstract:
Our purpose in this study was to evaluate the accuracy of a new multi-planar dose measurement method. The multi-planar dose distributions were reconstructed at each depth by convolution of EPID fluence and dose kernels with the use of EPIDose software (SunNuclear). The EPIDose was compared with EPID, MapCHECK (SunNuclear), EDR2 (Kodak), and Monte Carlo-calculated dose profiles. The EPIDose profiles were almost in agreement with Monte Carlo-calculated dose profiles and MapCHECK for test plans. The dose profiles were in good agreement with EDR2 at the penumbra region. For dose distributions, EPIDose, EDR2, and MapCHECK agreed with that of the treatment-planning system at each depth in the gamma analysis. In comparisons of clinical IMRT plans, EPIDose had almost the same accuracy as MapCHECK and EDR2. Because EPIDose has a wide dynamic range and high resolution, it is a useful tool for the complicated IMRT verification. Furthermore, EPIDose can also evaluate the absolute dose.
