Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Imaging Studies I: CT and MRI

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

Imaging Studies for Cardiovascular System V: CT

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

Imaging Biological Samples with Optical Microscopy

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

Imaging Studies VII: Vascular Imaging

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Global Workflow of a Comanipulation-Based Robotic System for Cervical Spine Surgery.

The international journal of medical robotics + computer assisted surgery : MRCAS·2026

Same author

Incorporating river morphodynamics in the characterization of key ecological system units for conservation in the western Amazon.

Scientific reports·2026

Same author

NNMT-driven metabolic reprogramming creates a NAMPT druggable vulnerability and reveals liquid biopsy biomarkers for TKI resistance in EGFR-mutant NSCLC.

Cancer letters·2025

Same author

Impact of clonal hematopoiesis on cardiovascular outcomes in cancer patients of the UK Biobank.

ESMO open·2025

Same author

Hospital discharges (MBDS) from Takotsubo syndrome in Spain. Regional differences (2008-2021).

Revista clinica espanola·2025

Same author

Ecteinascidin synthetic analogues: a new class of selective inhibitors of transcription, exerting immunogenic cell death in refractory malignant pleural mesothelioma.

Journal of experimental & clinical cancer research : CR·2024

Search research articles

Related Experiment Video

Updated: May 16, 2026

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Optical coherence tomography: from research to clinical application.

F Alfonso¹, J Sandoval, A Cárdenas

¹San Carlos University Hospital, Madrid, Spain. falf@hotmail.com

|December 12, 2012

Summary

This summary is machine-generated.

Optical coherence tomography (OCT) provides high-resolution intracoronary imaging for detailed atherosclerotic plaque analysis and intervention assessment. This advanced imaging tool enhances understanding of coronary artery disease and improves clinical decision-making.

More Related Videos

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

Related Experiment Videos

Last Updated: May 16, 2026

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

Area of Science:

Cardiovascular Imaging
Medical Technology
Biomedical Engineering

Background:

Optical coherence tomography (OCT) offers unprecedented spatial resolution (15 μm) for intracoronary imaging.
OCT provides detailed visualization of coronary microstructure and atherosclerotic plaque composition.
Its clinical use is expanding, establishing it as a robust research tool.

Purpose of the Study:

To highlight the capabilities of OCT in intracoronary imaging.
To demonstrate OCT's role in assessing plaque vulnerability and coronary interventions.
To underscore OCT's value in understanding coronary artery disease pathophysiology.

Main Methods:

Utilizing OCT's high spatial resolution for microstructure analysis.
Applying OCT for plaque composition assessment (lipid, fibrous, calcified).
Employing OCT to evaluate intervention outcomes (stent expansion, malapposition, dissection).

Main Results:

OCT accurately measures fibrous cap thickness and detects thin-cap fibroatheromas.
Plaque ruptures and thrombus are clearly identified in acute coronary syndromes.
OCT surpasses intravascular ultrasound in detecting minor stent deployment issues and assessing neointimal proliferation.

Conclusions:

OCT is crucial for accurate intracoronary plaque characterization and vulnerability assessment.
OCT significantly aids in evaluating and optimizing coronary interventions.
OCT is invaluable for unraveling stent failure mechanisms and advancing coronary artery disease research.