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Immunizations and pregnancy: an update for pharmacists
Erin C Raney1, Shareen Y El-Ibiary
1College of Pharmacy-Glendale, Midwestern University, Glendale, AZ , USA.
Journal of the American Pharmacists Association : Japha
|December 12, 2012
Summary
Vaccines during pregnancy are crucial for maternal and infant health. Live-attenuated vaccines are generally contraindicated, while inactivated vaccines like the influenza vaccine are recommended.
Area of Science:
- Obstetrics and Gynecology
- Immunology
- Pharmacology
Background:
- Immunizations are vital for women of childbearing age.
- Vaccine safety during pregnancy is a critical consideration for public health.
Purpose of the Study:
- To review the safety profile of various immunizations during pregnancy.
- To provide guidance on appropriate vaccine use in pregnant individuals.
Main Methods:
- Conducted a PubMed search using keywords: vaccine, immunizations, and pregnancy.
- Reviewed current national guidelines on vaccine administration during pregnancy.
Main Results:
- Live-attenuated vaccines (e.g., MMR, varicella) are contraindicated due to theoretical fetal risks.
- Trivalent inactivated influenza vaccine is recommended for pregnant women during flu season.
- Hepatitis B, tetanus-diphtheria-acellular pertussis (Tdap), and certain travel vaccines can be safely administered based on risk criteria.
- All routine adult vaccines are compatible with breastfeeding.
- Smallpox and yellow fever vaccines require specific risk-benefit assessment.
Conclusions:
- Pharmacists are essential in guiding safe and appropriate vaccine recommendations before and during pregnancy.
- Adherence to updated guidelines ensures optimal maternal and fetal protection.
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