Related Experiment Video
Updated: May 16, 2026

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders
Published on: February 3, 2021
Adenosine-induced worsening of supraventricular tachycardia
Georgey Koshy Kunnumpuram1, Ashfaq Patel
1Department of Cardiology, Al Ahli Hospital, Doha, Qatar.
Abstract:
An approximately 20-year-old to 30-year-old patient presented with a haemodynamically stable supraventricular tachycardia . The patient was managed with intravenous adenosine primarily, with two bolus doses of 6 and 12 mg. This, however, caused a rare paradoxical surge of tachycardia with mild haemodynamic compromise. The patient further required a combination of Metoprolol and Verapamil administration to slow down and reverse the arrhythmia. Following this the patient remained stable with no further episodes till discharge.
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