Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Do patients with otitis externa produce biochemically different cerumen?

J E Osborne1, J D Baty

  • 1Department of Otolaryngology, Ninewells Hospital, Dundee, UK.

Clinical Otolaryngology and Allied Sciences
|February 1, 1990
PubMed
Summary

Polyunsaturated fatty acids (PUFAs) show antibacterial properties. However, this study found no significant difference in fatty acid ratios in earwax between patients with recurrent otitis externa and healthy individuals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SWR/J mice are susceptible to alkylator-induced myeloid leukemia.

Blood cancer journal·2013
Same author

Antinuclear antibodies associate with loss of response to antitumour necrosis factor-α therapy in psoriasis but do not necessarily predict treatment failure.

The British journal of dermatology·2010
Same author

Objective evaluation of tongue base snoring after the use of an oral appliance: a prospective case series.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·2009
Same author

Demographic and clinical correlates of extent of psoriasis during stable disease and during flares in chronic plaque psoriasis.

The British journal of dermatology·2008
Same author

Do we need a revised public health policy on sun exposure?

The British journal of dermatology·2007
Same author

In silico analysis of the 5' region of the Vitamin D receptor gene: functional implications of evolutionary conservation.

The Journal of steroid biochemistry and molecular biology·2007

Area of Science:

  • Biochemistry
  • Microbiology
  • Otolaryngology

Background:

  • Polyunsaturated fatty acids (PUFAs) possess demonstrated antibacterial properties.
  • Earwax (cerumen) composition may influence susceptibility to external ear infections.
  • Recurrent otitis externa is a common condition often requiring medical intervention.

Purpose of the Study:

  • To investigate the potential role of fatty acid composition in the cerumen of individuals with recurrent otitis externa.
  • To compare the ratio of unsaturated to saturated fatty acids in cerumen between patients and healthy controls.

Main Methods:

  • Cerumen samples were collected from seven patients diagnosed with recurrent otitis externa.
  • Cerumen samples were also collected from seven unaffected control subjects.

Related Experiment Videos

  • Gas chromatography was employed to analyze the fatty acid profiles of all cerumen samples.

    • Main Results:

    • Analysis revealed no statistically significant difference in the overall unsaturated/saturated fatty acid ratio between the two groups.
    • Individual fatty acid amounts in the cerumen also showed no significant variations between patients with recurrent otitis externa and controls.

    Conclusions:

    • The findings do not support a link between altered cerumen fatty acid composition and the occurrence of recurrent otitis externa.
    • Further research may be needed to explore other factors contributing to the pathogenesis of this condition.