Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

COPD: Management Using Bronchodilators and Corticosteroids

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

Pneumonia I: Introduction

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Walking the tightrope: Balancing immune checkpoints and their inhibitors in host defence against bacterial infections.

Journal of applied biomedicine·2026

Same author

Complications and long-term sequelae of tick-borne encephalitis: association with age and other predictors - a multicenter observational study.

Ticks and tick-borne diseases·2026

Same author

Response to: Comment on: Detection of tick-borne encephalitis virus RNA in patient samples at different stages of infection.

The Journal of infection·2026

Same author

Chronic pulmonary aspergillosis complicating pulmonary cystic echinococcosis: a global systematic review.

Therapeutic advances in infectious disease·2026

Same author

Reaffirming the importance of nomenclature stability for <i>Candida auris</i> and its associated disease of candidiasis.

Journal of clinical microbiology·2025

Same author

Genome-wide association study identifies <i>ABCG1</i> as a susceptibility locus for tick-borne encephalitis.

iScience·2025

Search research articles

Related Experiment Video

Updated: May 16, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Aspergillus bronchitis without significant immunocompromise.

Ales Chrdle¹, Sahlawati Mustakim, Rowland J Bright-Thomas

¹The National Aspergillosis Center, University Hospital of South Manchester, Manchester, UK.

Annals of the New York Academy of Sciences

|December 13, 2012

Summary

This summary is machine-generated.

Aspergillus bronchitis, a distinct lung condition in patients with structural lung disease, may respond to antifungal therapy. This study clarifies its characteristics and differentiates it from other Aspergillus-related conditions.

Related Experiment Videos

Last Updated: May 16, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Area of Science:

Pulmonology
Mycology
Infectious Diseases

Background:

Aspergillus bronchitis remains poorly understood, lacking clear diagnostic criteria.
This study investigates clinical data from over 400 patients with persistent chest symptoms, excluding other forms of aspergillosis.

Observation:

Seventeen patients met criteria for Aspergillus bronchitis, predominantly women (14) with a mean age of 57.
Common symptoms included productive cough (16), voluminous sputum (8), and recurrent chest infections (7).
Underlying conditions included bronchiectasis (12) and significant dyspnea (8).

Findings:

Aspergillus fumigatus (13), A. niger (3), and A. terreus (1) were identified.
Elevated Aspergillus IgG (71%) and precipitins (29%) were observed.
Antifungal therapy showed a major response in 50% of patients, with a 42% relapse rate.

Implications:

Aspergillus bronchitis is a distinct clinical entity in non-immunocompromised patients with structural lung disease.
It differs from asymptomatic colonization and other invasive or allergic aspergillosis forms.
Antifungal treatment can be effective, though long-term management may be necessary due to relapse potential.