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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: May 16, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

Deep brain stimulation for neurological disorders.

Chima O Oluigbo1, Asem Salma, Ali R Rezai

  • 1Department of Neurosurgery and the Center for Neuromodulation, The Ohio State University Medical Center, Columbus, OH 43210, USA.

IEEE Reviews in Biomedical Engineering
|December 13, 2012
PubMed
Summary

Deep brain stimulation (DBS) offers a reversible and adjustable treatment for movement disorders like Parkinson's disease. This promising neuromodulation technique is also being explored for various neurological and psychiatric conditions.

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Last Updated: May 16, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

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Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
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Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

Area of Science:

  • Neurosurgery
  • Neurology
  • Biomedical Engineering

Background:

  • Deep brain stimulation (DBS) is a well-established surgical treatment for advanced, medication-intractable movement disorders.
  • It involves delivering electrical impulses to specific brain regions to modulate neural activity.

Purpose of the Study:

  • To review the current applications and potential of Deep Brain Stimulation (DBS).
  • To highlight the advantages of DBS over previous lesioning procedures.

Main Methods:

  • Review of clinical investigations and existing literature on DBS.
  • Analysis of the adjustable parameters and reversible nature of DBS systems.

Main Results:

  • DBS is a proven therapy for Parkinson's disease, essential tremor, and dystonia.
  • Ongoing research explores DBS for epilepsy, depression, OCD, addiction, obesity, Alzheimer's, and TBI.

Conclusions:

  • Deep brain stimulation (DBS) is a highly promising neuromodulation technique with significant potential for treating a wide range of challenging neurological and psychiatric disorders.
  • Its adjustable and reversible nature offers distinct advantages over older ablative techniques.