Pulmonary hamartoma syndrome

We reviewed 24 charts of patients with pulmonary hamartoma; numerous congenital anomalies and benign tumors were observed in this series. Most of the observed associations are known to occur in patients with Cowden's syndrome, which is characterized by multiple hamartomatous neoplasms of ectodermal, mesodermal, and endodermal origin; however, to our knowledge, there has been no reported association between pulmonary hamartoma and Cowden's syndrome. We conclude that pulmonary hamartomas are frequently accompanied by other developmental abnormalities and benign tumors.