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Related Concept Videos

Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
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Obesity01:24

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z Scores and Area Under the Curve01:17

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z scores are the standardized values obtained after converting a normal distribution into a standard normal distribution. A z score is measured in units of the standard deviation. The z score tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a z score of zero.
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Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

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Published on: February 2, 2017

Correlation between birth weight and maternal body composition.

Etaoin Kent1, Vicky O'Dwyer, Chro Fattah

  • 1UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland. ekent@rcsi.ie

Obstetrics and Gynecology
|December 13, 2012
PubMed
Summary

Maternal fat-free mass, not fat mass, predicts higher birth weight in nondiabetic pregnancies. Interventions targeting fat mass may not prevent large-for-gestational-age neonates.

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Published on: September 22, 2023

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Body Composition Analysis

Background:

  • Maternal body composition influences fetal growth.
  • Accurate prediction of birth weight is crucial for optimal pregnancy management.
  • First-trimester body composition assessment may offer predictive insights.

Purpose of the Study:

  • To identify maternal body composition parameters measured in early pregnancy that predict increased birth weight.
  • To investigate the association between fat mass, fat-free mass, and large-for-gestational-age neonates.

Main Methods:

  • Recruitment of nondiabetic women with singleton pregnancies in the first trimester.
  • Measurement of maternal body composition using multifrequency segmental bioelectric impedance analysis.
  • Application of multivariable linear and logistic regression analyses to determine predictors of birth weight and macrosomia.

Main Results:

  • Fat-free mass was a significant positive predictor of birth weight (standardized β=0.237, P<.001).
  • Maternal fat mass did not show a significant relationship with birth weight.
  • Women in the highest fat-free mass quartile had an adjusted odds ratio of 3.64 for delivering a neonate weighing over 4 kg.

Conclusions:

  • Maternal fat-free mass, rather than adiposity, is positively correlated with birth weight.
  • Current interventions aimed at reducing maternal fat mass or modifying gestational weight gain guidelines may not effectively prevent large-for-gestational-age neonates in this population.