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Updated: May 16, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Opioid addiction in pregnancy.
Scott A Shainker1, Kelley Saia, Aviva Lee-Parritz
1Boston University School of Medicine, Department of Obstetrics and Gynecology, Boston Medical Center, Boston, MA 02118, USA. scott.shainker@bmc.org
Opioid addiction in pregnancy poses risks to mothers and babies. Buprenorphine is a safe alternative to methadone for maintenance treatment, and breastfeeding is encouraged.
Area of Science:
- Obstetrics and Gynecology
- Addiction Medicine
- Neonatal Care
Background:
- Opioid dependence during pregnancy presents significant maternal and fetal risks.
- Healthcare providers including obstetricians, gynecologists, and addiction specialists need updated guidance.
- Multidisciplinary care models are essential for managing pregnant patients with opioid dependence.
Purpose of the Study:
- To review the incidence, risks, and complications of opioid addiction in pregnancy.
- To discuss available maintenance treatment options for opioid-dependent pregnant individuals.
- To compare the safety and efficacy of methadone and buprenorphine in this population.
Main Methods:
- This is a review article synthesizing current literature and clinical recommendations.
- Data on treatment options, risks, and outcomes were analyzed.
- Expert consensus and emerging research were considered.
Main Results:
- Opioid dependence in pregnancy is associated with substantial maternal and fetal risks.
- Buprenorphine is emerging as a safe and effective alternative to methadone for maintenance therapy.
- Neonatal Abstinence Syndrome (NAS) is common, necessitating prolonged neonatal hospitalization.
- Breastfeeding is recommended, and postpartum pain management requires special attention.
Conclusions:
- A multidisciplinary approach is crucial for managing opioid-dependent pregnant patients.
- Buprenorphine offers a safe and effective maintenance treatment option.
- Comprehensive postpartum care and transition to addiction specialists are vital for long-term recovery and well-being.
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