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Published on: January 11, 2020
[Delirium and multimorbidity in the elderly]
1Klinik für Alterspsychiatrie, Psychiatrische Universitätsklinik Zürich. egemen.savaskan@puk.zh.ch
Abstract:
Delirium is an acute confusion state of multifactorial genesis, commonly seen in the elderly with multimorbidity. Age and dementia, followed by infections and polypharmacy, are known as the most important risk factors. Increased disease interactions and medication use in the multimorbid elderly might precipitate delirium. Serious consequences of multimorbidity often are psychiatric diseases such as depression. Also anxiety and schizoprenia show a high comorbidity with somatic diseases. The therapy of elderly multimorbid patients is risky and must be preceded by profound assessment of all pathogenic factors. Pharmacotherapy needs an ongoing screening for side effects and indication.
Insights
Delirium, an acute confusion state in elderly patients with multiple health conditions, is often caused by age, dementia, infections, and polypharmacy. Careful assessment and medication review are crucial for managing these complex cases.
Area of Science:
- Geriatrics
- Internal Medicine
- Psychiatry
Context:
- Delirium is a common acute confusion state in elderly individuals with multimorbidity.
- Key risk factors include advanced age, dementia, infections, and polypharmacy.
- Multimorbidity increases the risk of complex disease interactions and medication-related issues, precipitating delirium.
Purpose:
- To highlight the multifactorial genesis of delirium in the elderly.
- To emphasize the significant risk factors associated with multimorbidity.
- To underscore the necessity of thorough assessment and cautious pharmacotherapy in this population.
Summary:
- Delirium in the elderly is multifactorial, with age, dementia, infections, and polypharmacy as primary drivers.
- Increased disease burden and medication use in multimorbid elderly patients heighten delirium risk.
- Psychiatric conditions like depression, anxiety, and schizophrenia frequently co-occur with somatic diseases.
Impact:
- Therapy for elderly multimorbid patients requires comprehensive assessment of all pathogenic factors.
- Pharmacotherapy necessitates continuous screening for side effects and appropriate indications.
- Improved understanding can lead to better management strategies for delirium in the elderly.
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