Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Disorders of Hemostasis

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.

Blood Studies I: ABG and VBG

Blood Studies I: ABG and VBG

Blood studies are critical in the medical field, enabling healthcare professionals to assess a patient's health status accurately. This page will focus on two significant blood studies: Arterial Blood Gas (ABG) and Venous Blood Gas (VBG).
Arterial Blood Gas (ABG)
Arterial Blood Gas (ABG) studies are crucial for assessing the lungs' ability to supply oxygen and remove carbon dioxide, reflecting the patient's ventilation status. They also help understand the kidneys' capacity to reabsorb or...

Pre-Procedural Guidelines for Assessing Blood Pressure

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...

Errors occurring during blood pressure monitoring

Errors occurring during blood pressure monitoring

Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...

Blood Transfusion

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Patterns of hormonal contraception use in women with sickle cell disease and employer-sponsored insurance.

Contraception·2026

Same author

The interplay of von Willebrand disease and women's reproductive health.

Blood advances·2025

Same author

Reflections on Sperm Banking Decisions and Support Needs Among Adolescent Males and Their Caregivers 1 Year After Cancer Diagnosis: A Qualitative Study.

Pediatric blood & cancer·2025

Same author

High Rates of Post-Tonsillectomy Hemorrhage in Children With von Willebrand Disease.

Pediatric blood & cancer·2025

Same author

Understanding Acute Heavy Menstrual Bleeding: Insights From an Interdisciplinary Panel.

O&G open·2025

Same author

Sustained Engagement and Usability of a Mobile App to Study Menstrual Cycles in Young Adolescents.

Journal of pediatric and adolescent gynecology·2025

Same journal

CAR T-cell therapy and bispecific antibodies in the management of multiple myeloma.

Hematology. American Society of Hematology. Education Program·2025

Same journal

Emerging immunotherapy advances for non-Hodgkin lymphomas: engaging T cells in the fight.

Hematology. American Society of Hematology. Education Program·2025

Same journal

Anticoagulants in hematologic malignancies: what is the data?

Hematology. American Society of Hematology. Education Program·2025

Same journal

Diagnosis and management of cold agglutinin disease.

Hematology. American Society of Hematology. Education Program·2025

Same journal

What to know about rare B-cell malignancies in 2025.

Hematology. American Society of Hematology. Education Program·2025

Same journal

Peri-transplant conundrums: optimizing maintenance therapy using MRD-directed approaches.

Hematology. American Society of Hematology. Education Program·2025

See all related articles

Search research articles

Related Experiment Video

Updated: May 16, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

Bleeding scores: are they really useful?

Sarah H O'Brien¹

¹Center for Innovation in Pediatric Practice, The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA. OBrien@nationwidechildrens.org

Hematology. American Society of Hematology. Education Program

|December 13, 2012

Summary

This summary is machine-generated.

Bleeding scores precisely quantify bleeding symptoms, aiding in diagnosing mild bleeding disorders when lab tests are limited. These validated tools help differentiate patients and may be integrated with lab results for universal diagnosis.

Related Experiment Videos

Last Updated: May 16, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

Area of Science:

Hematology
Clinical Diagnostics

Background:

Mild bleeding disorders are common, yet current laboratory tests have diagnostic limitations.
Precise quantification of bleeding symptoms is increasingly important for accurate diagnosis.

Purpose of the Study:

To review the development and application of bleeding assessment tools.
To discuss the refinement, limitations, and future potential of bleeding scores in diagnosing mild bleeding disorders.

Main Methods:

Review of validated research tools like the Vicenza bleeding score and Pediatric Bleeding Questionnaire.
Analysis of recent publications on the application and refinement of these bleeding assessment instruments.

Main Results:

Bleeding scores effectively discriminate between healthy individuals and those with von Willebrand disease (VWD).
Condensed bleeding scores show promise for increased clinical applicability.
These tools aid in evaluating patients with suspected inherited mild bleeding disorders.

Conclusions:

Bleeding assessment tools are valuable for diagnosing mild bleeding disorders.
Further research is needed to refine these scores and explore their clinical applications.
Integration of bleeding scores with laboratory testing could lead to a universal diagnostic approach.