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Reference values for renal size obtained from MAG3 scintigraphy.

Andrew T Taylor1, Neeta Shenvi, Russell D Folks

  • 1Department of Radiology and Imaging Sciences, School of Medicine, Emory University, Atlanta, GA 30322, USA. andrew.taylor@emory.edu

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This study established reference values for kidney size using 99mTc-MAG3 renal scintigraphy. Regression equations were derived to predict normal renal size limits, aiding in detecting unexpected changes in kidney dimensions.

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Area of Science:

  • Nuclear Medicine
  • Radiology
  • Nephrology

Background:

  • Renal size assessment is crucial for diagnosing kidney diseases.
  • Standardized reference values for renal size from 99mTc-MAG3 renal scintigraphy are lacking.
  • Accurate assessment of renal size aids in detecting bilateral renal abnormalities.

Purpose of the Study:

  • To establish reference values for renal size using 99mTc-MAG3 renal scintigraphy.
  • To derive regression equations for predicting normal renal size limits.
  • To aid in the detection of unsuspected bilateral increases or decreases in renal size.

Main Methods:

  • 106 subjects undergoing 99mTc-MAG3 renal scintigraphy for kidney donation evaluation were studied.
  • Renal length, width, and area were measured from scintigraphic images.
  • Quantile regression was used to correlate renal dimensions with patient sex, height, weight, BMI, and body surface area (BSA).

Main Results:

  • Mean kidney lengths were established for male and female patients.
  • Sex was not a significant factor in the regression models for renal size.
  • Regression equations were derived to define the 5th and 95th percentiles for renal length and area based on BSA.

Conclusions:

  • Developed regression equations define upper and lower limits of renal size from 99mTc-MAG3 images.
  • These equations can assist in identifying unexpected bilateral changes in renal size.
  • Provides a valuable tool for quantitative assessment of renal dimensions in clinical practice.