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Alterations in Muscle Tone lll01:11

Alterations in Muscle Tone lll

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Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
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Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke
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Grey matter changes in motor conversion disorder.

Selma Aybek1, Timothy R J Nicholson, Bogdan Draganski

  • 1Section of Cognitive Neuropsychiatry, Institute of Psychiatry, King's College London, , London, UK.

Journal of Neurology, Neurosurgery, and Psychiatry
|December 14, 2012
PubMed
Summary
This summary is machine-generated.

Patients with motor conversion disorder (CD) show increased cortical thickness in premotor areas. These brain structure changes may indicate vulnerability or disease-related plasticity.

Keywords:
NeuropsychiatryNeuroradiology

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Published on: July 31, 2019

Area of Science:

  • Neuroscience
  • Neurology
  • Radiology

Background:

  • Motor conversion disorder (CD) is a neurological condition affecting motor function.
  • Previous research often assumed normal brain anatomy in CD.

Purpose of the Study:

  • To identify anatomical brain differences in motor processing areas between motor CD patients and healthy controls.
  • To investigate structural changes in patients with hemiparetic and paraparetic CD.

Main Methods:

  • T1-weighted 3T brain MRI scans were acquired from 15 motor CD patients and 25 controls.
  • Voxel-based morphometry (VBM) and voxel-based cortical thickness (VBCT) analyses were employed.

Main Results:

  • Significant increases in bilateral premotor cortex cortical thickness were observed in hemiparetic CD patients compared to controls.
  • A trend towards increased grey matter volume in the same region was noted.
  • Cortical thickness changes showed a non-significant positive correlation with symptom severity and illness duration.

Conclusions:

  • Altered brain structure, specifically increased cortical thickness in premotor areas, is evident in hemiparetic CD.
  • These findings challenge the assumption of normal brain anatomy in CD.
  • The observed changes may reflect either premorbid vulnerability or disease-related neural plasticity.