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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
[Mental illness and pregnancy]
Gisèle Apter1, Valérie Garez, François Medjkane
1Etablissement public de santé Erasme, 7e secteur de psychiatrie infanto-juvénile, unité de recherche RePPEr, GERI université Paris-Ouest Nanterre, unité PPUMMA, 92160 Antony, France. gisdanap@aol.com
Pregnancy was once thought a period of bliss devoid of mental illness. We now know this is not so. It is well documented that pregnancy and the peripartum are not only a time when preexisting mental illness will persist but that it is also a high-risk period for renewed episodes of mental illness, whether de novo or relapse. In this paper, we will describe the three main axis of management of maternal mental illness during the peripartum: maternal psychiatric illness, fetal, neonatal and infant development and future mother-infant relationship. We will give an overview of how to organize care for mothers with schizophrenia and bipolar disorder. Good practice management of psychotropic medication during this period will be described. Finally the importance of networking and multidisciplinary management of these situations will be underlined.
Pregnancy was once thought a period of bliss devoid of mental illness. We now know this is not so. It is well documented that pregnancy and the peripartum are not only a time when preexisting mental illness will persist but that it is also a high-risk period for renewed episodes of mental illness, whether de novo or relapse. In this paper, we will describe the three main axis of management of maternal mental illness during the peripartum: maternal psychiatric illness, fetal, neonatal and infant development and future mother-infant relationship. We will give an overview of how to organize care for mothers with schizophrenia and bipolar disorder. Good practice management of psychotropic medication during this period will be described. Finally the importance of networking and multidisciplinary management of these situations will be underlined.
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