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Updated: May 16, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

Depressed atrial function in diastolic dysfunction: a speckle tracking imaging study.

Umar A Khan¹, Giovanni de Simone, Jeffrey Hill

¹Division of Cardiovascular Disease, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.

Echocardiography (Mount Kisco, N.Y.)

|December 15, 2012

Summary

This summary is machine-generated.

Left atrial (LA) strain, measured by speckle tracking imaging (STI), is significantly reduced in patients with early diastolic dysfunction (DD). This reduced LA strain indicates impaired atrial distensibility and is a better marker for DD than LA enlargement.

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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

Area of Science:

Cardiology
Medical Imaging
Echocardiography

Background:

Two-dimensional speckle tracking imaging (STI) is a novel method for assessing left atrial (LA) reservoir function.
Diastolic dysfunction (DD) is a condition affecting heart relaxation, and its relationship with LA function requires further investigation.

Purpose of the Study:

To investigate left atrial (LA) strain using STI in patients with diastolic dysfunction (DD).
To determine if LA strain abnormalities are integral to the pathogenesis of DD.

Main Methods:

STI was applied to 50 patients with Grade 1-2 DD and 100 normal controls.
Doppler analysis of filling, E/e' (as a surrogate for LA pressure), and LA stiffness index were performed.

Main Results:

Patients with DD exhibited higher E/e', greater LA volume, and increased LA stiffness compared to controls.
DD patients showed a lower E/A ratio and significantly reduced global LA strain.
Reduced LA strain was observed even after correction for LA volume and E/A ratio, suggesting it's an independent marker.

Conclusions:

Left atrial (LA) strain is significantly reduced in early diastolic dysfunction (DD).
Reduced LA strain is associated with increased LA stiffness and LA size.
Impaired atrial distensibility is suggested by reduced LA strain, independent of LA volume.