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Diphtheria with a difference--a rare Corynebacterium fatality with associated apoptotic cell death
M D Leek1, S Sivaloganathan, S K Devaraj
1Department of Forensic Medicine, University of Leeds, UK.
Histopathology
|February 1, 1990
Summary
Corynebacterium ulcerans infection caused the sudden death of a healthy woman. This is the first reported fatality from C. ulcerans, unlike the more common Corynebacterium diphtheriae.
Area of Science:
- Infectious Diseases
- Bacteriology
- Pathogen Research
Background:
- Corynebacterium diphtheriae infections are a known cause of mortality.
- Corynebacterium ulcerans is a related bacterial species with zoonotic potential.
Observation:
- A previously healthy 73-year-old woman experienced sudden death.
- The cause of death was identified as an infection with Corynebacterium ulcerans.
Findings:
- Fatalities due to Corynebacterium diphtheriae are well-documented.
- This case represents the first reported death attributed to Corynebacterium ulcerans infection.
Implications:
- Highlights the potential lethality of Corynebacterium ulcerans.
- Underscores the importance of recognizing C. ulcerans as a potential cause of severe disease.
- May prompt further investigation into the pathogenicity and clinical spectrum of C. ulcerans.