Related Experiment Video
Updated: May 16, 2026

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
Intermediate uveitis, an ophthalmological manifestation of systemic disease
V Poindron1, G Camuset, D Krencker
1Clinical immunology and internal medicine, National reference Center for Rare Autoimmune Diseases, CHRU Strasbourg, university of Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg cedex, France. Vincent.poindron@chru-strasbourg.fr
Purpose:
Intermediate uveitis is frequently indicative associated with systemic disease. In addition to the initial evaluation of the patient with intermediate uveitis, we sought to determine the role of longitudinal follow-up in improving the diagnosis of systemic disease associated with intermediate uveitis.
Method:
Retrospective analysis of a cohort of 51 patients with intermediate uveitis followed for 5 to 13 years.
Results:
Upon initial evaluation, an underlying disease associated with the intermediate uveitis was found in nine out of the 51 patients. Among the remaining patients, after at least 5 years of follow-up, eight new associated diagnoses were revealed (primarily inflammatory diseases and cancers).
Conclusion:
These results suggest that the initial work-up of the patient with intermediate uveitis is not sufficiently sensitive and that careful follow-up of these patients considerably improves the diagnosis of associated disease.
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