[NAD+-converting enzymes in neuronal and glial cells: CD38 as a novel target for neuroprotection]
Vestnik Rossiiskoi Akademii Meditsinskikh Nauk
|December 18, 2012
Abstract:
The review contains current data on molecular mechanisms which control NAD+ homeostasis in brain cells. It also deals with the role of NAD+-converting enzymes in regulation of functional activity, viability and intercellular communication of neuronal and glial cells. Special attention is paid to involvement of CD38 into regulation of NAD+ levels in brain cells in normal and pathological conditions.
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