[Current problems of combined use of vaccination and non-immunological methods for infection control]

Based on data analysis on the morbidity rates and dynamics of the vaccine-preventable infectious diseases in Russia in comparison with those, immune-prophylaxis methods of which have not been developed yet, the need is shown to intensify efforts on generation and application disinfectological technologies and non-specific prophylactic means in addition to the missing vaccinological ones. First of all, this is necessary to control salmonella infections, different hemorrhagic fevers, sexually transmitted diseases, lice and, especially, mass acute respiratory diseases, upper respiratory infections, multiple unrecorded localization and etiology, annual contribution of which to total infection morbidity is 86-93%. Studies and development of this area of prevention and control of "uncontrolled" infections requires efforts both of disinfectologists and professionals in hygiene, epidemiology, microbiology, chemistry, bio-technology, entomology etc. Under these conditions, all infections can and shall become "controlled" through combined application of immunological and non-immunological methods and means generated and assessed on the basis of principles of the evidence-based medicine.