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Updated: May 16, 2026
08:34
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Management of radiation proctitis.
William M Mendenhall1, Brian T McKibben, Bradford S Hoppe
1*University of Florida Proton Therapy Institute †St Vincent's Healthcare, Jacksonville, FL.
American Journal of Clinical Oncology
|December 18, 2012
Summary
Managing radiation proctitis requires a conservative approach. Interventions should be minimally invasive, avoiding rectal biopsies and reserving aggressive treatments for refractory cases.
Area of Science:
- Gastroenterology
- Radiation Oncology
Background:
- Radiation proctitis is a common complication of pelvic radiotherapy.
- Current management strategies for radiation proctitis are not well-established.
Purpose of the Study:
- To review and outline optimal management strategies for radiation proctitis.
- To discuss conservative and interventional treatment options.
Main Methods:
- Review of available literature on radiation proctitis management.
- Discussion of topical agents (sucralfate enemas, formalin), oral agents (pentoxyfylline, vitamin A), hyperbaric oxygen, and endoscopic interventions (argon plasma coagulation).
Main Results:
- Conservative management is recommended initially.
- Rectal biopsies should be avoided due to complication risk.
- Endoscopic interventions like argon plasma coagulation are considered for refractory cases.
Conclusions:
- A stepwise approach to radiation proctitis management is advised, starting with conservative measures.
- Minimally invasive options should be prioritized to avoid exacerbating symptoms.
- Aggressive treatments are reserved for cases unresponsive to conservative and less invasive therapies.
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