Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Larynx01:21

Larynx

The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway interventions are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of an e-Health Software for Speech and Swallowing Rehabilitation Following Laryngectomy.

Laryngoscope investigative otolaryngology·2025
Same author

[Molecular laryngology : A new chapter in the understanding of laryngeal diseases].

HNO·2021
Same author

Comprehensive investigation of saliva replacement liquids for the treatment of xerostomia.

International journal of pharmaceutics·2019
Same author

Exploring stimulation patterns for electrical stimulation of the larynx using surface electrodes.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2019
Same author

Sex differences in coronary artery plaque composition detected by coronary computed tomography: quantitative and qualitative analysis.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2019
Same author

Towards an in vitro fibrogenesis model of human vocal fold scarring.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2018

Related Experiment Video

Updated: May 16, 2026

Construction and Characterization of a Novel Vocal Fold Bioreactor
11:11

Construction and Characterization of a Novel Vocal Fold Bioreactor

Published on: August 1, 2014

[Vocal fold scars: pathogenesis, diagnosis, therapy].

G Friedrich1, M Gugatschka

  • 1Klinische Abteilung für Phoniatrie, HNO-Universitätsklinik Graz, Medizinische Universität Graz, Österreich. gerhard.friedrich@klinikum-graz.at

HNO
|December 18, 2012
PubMed
Summary
This summary is machine-generated.

Vocal fold scarring impairs voice function, leading to reduced vocal capacity. Current treatments require individualized approaches, with new techniques like laser therapy and tissue engineering showing promise but not yet in routine clinical use.

More Related Videos

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
09:58

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp

Published on: February 3, 2014

Manufacturing Process for Non-Adhesive Super-Soft Vocal Fold Models
06:24

Manufacturing Process for Non-Adhesive Super-Soft Vocal Fold Models

Published on: January 5, 2024

Related Experiment Videos

Last Updated: May 16, 2026

Construction and Characterization of a Novel Vocal Fold Bioreactor
11:11

Construction and Characterization of a Novel Vocal Fold Bioreactor

Published on: August 1, 2014

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
09:58

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp

Published on: February 3, 2014

Manufacturing Process for Non-Adhesive Super-Soft Vocal Fold Models
06:24

Manufacturing Process for Non-Adhesive Super-Soft Vocal Fold Models

Published on: January 5, 2024

Area of Science:

  • Laryngology and phonosurgery
  • Vocal fold microstructure and vibration

Context:

  • Vocal fold scarring significantly impacts vocal capacity and quality.
  • Existing treatments for scarred vocal folds remain a challenge in laryngology.
  • Pathophysiology of vocal fold scarring is increasingly understood, yet effective treatments are limited.

Purpose:

  • To review the current understanding and treatment strategies for scarred vocal folds.
  • To highlight the need for multidimensional, individualized treatment concepts.
  • To discuss emerging therapeutic modalities and their clinical potential.

Summary:

  • Scarring disrupts vocal fold microstructure, impairing vibration and causing glottic insufficiency and dysphonia.
  • Treatment necessitates a comprehensive approach combining surgical and non-surgical options.
  • Phonosurgical techniques include medialization, epithelium-freeing procedures, injection augmentation, and buccal mucosa grafting.

Impact:

  • Individualized, multidimensional treatment concepts are crucial for managing scarred vocal folds.
  • Novel treatments like angiolytic lasers and tissue engineering offer future therapeutic avenues.
  • Despite promising preliminary results, advanced techniques require further validation for clinical integration.