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Related Concept Videos

Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Dementia01:30

Dementia

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The progression of dementia is generally gradual.
Brain Imaging01:14

Brain Imaging

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Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Alzheimer's Disease: Overview01:26

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Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
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Published on: April 18, 2025

Dementia and neuroimaging.

Federica Agosta1, Francesca Caso, Massimo Filippi

  • 1Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, via Olgettina 60, 20132 Milan, Italy.

Journal of Neurology
|December 18, 2012
PubMed
Summary
This summary is machine-generated.

Accurate diagnosis and monitoring of dementia are crucial for effective treatment. Advanced neuroimaging techniques, including MRI and PET scans, aid in early detection and differentiation of dementing conditions.

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Using Retinal Imaging to Study Dementia
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Using Retinal Imaging to Study Dementia

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Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Early diagnosis and monitoring of dementing conditions are critical for patient care and research.
  • Disease-modifying therapies for dementia are advancing, increasing the need for precise diagnostic tools.
  • Neuroimaging is essential for identifying reversible causes of dementia and characterizing specific dementia syndromes.

Purpose of the Study:

  • To review recent findings on the use of neuroimaging in studying dementing conditions.
  • To highlight the role of conventional and advanced imaging techniques in dementia research.
  • To provide an overview of new imaging modalities for assessing brain structure and function.

Main Methods:

  • Review of recent papers published in the Journal of Neurology.
  • Analysis of studies employing conventional neuroimaging techniques.
  • Evaluation of research utilizing advanced neuroimaging modalities like PET and MRI.

Main Results:

  • Neuroimaging effectively detects reversible causes of dementia.
  • Structural and functional signatures identified through imaging aid in differentiating dementia syndromes.
  • Advanced techniques like diffusion tensor MRI and functional MRI offer detailed insights into brain changes.

Conclusions:

  • Neuroimaging plays a pivotal role in the diagnosis and monitoring of dementia.
  • Emerging imaging technologies enhance the characterization and differentiation of various dementing conditions.
  • Continued research using advanced neuroimaging is vital for improving dementia care.