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Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

[Generalized cutaneous candidiasis in newborn at term]

Husein Husein El Ahmed1, Guillermo Arturo Cañadas-De la Fuente, Rafael Fernández-Castillo

  • 1Hospital Universitario San Cecilio, Granada, España.

Biomedica : Revista Del Instituto Nacional De Salud
|December 18, 2012
PubMed

Insights

Congenital cutaneous candidiasis can be transmitted during birth from mother to child. Early diagnosis of Candida albicans infection in newborns is crucial to prevent severe complications like sepsis.

Area of Science:

  • Neonatal infections
  • Dermatology
  • Mycology

Background:

  • Cutaneous candidiasis affects both children and adults, with varying prevalent species.
  • Infections can be localized or systemic, caused by multiple etiological agents.

Observation:

  • A full-term newborn developed congenital cutaneous candidiasis 24 hours after birth.
  • The infant was exposed to a subclinical vaginal candidiasis infection during delivery.

Findings:

  • The etiological agent was identified as Candida albicans, leading to sepsis and respiratory distress.
  • Blood tests revealed elevated C-reactive protein (CRP) and leukocytosis with left shift.
  • Cutaneous biopsy confirmed candidiasis, while blood cultures identified Staphylococcus aureus.

Implications:

  • This case highlights the transmission of Candida albicans from mother to neonate during birth.
  • Prompt diagnosis and management are essential to avert serious neonatal complications.
  • Emphasizes the importance of screening for vaginal candidiasis in pregnant women to prevent neonatal transmission.
Abstract

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