Related Experiment Video

Updated: May 16, 2026

Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis
10:23

Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis

Published on: April 17, 2017

Sexually transmitted hepatitis C infection: the new epidemic in MSM?

Daniel Bradshaw1, Gail Matthews, Mark Danta

  • 1Viral Hepatitis and Clinical Research Program, Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia.

Current Opinion in Infectious Diseases
|December 18, 2012
PubMed
Abstract

Insights

Hepatitis C (HCV) is increasingly transmitted via mucosal routes among HIV-infected men who have sex with men (MSM). Understanding this transmission is key to developing effective public health interventions.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Virology

Background:

  • Hepatitis C virus (HCV) infection poses a growing concern among HIV-infected men who have sex with men (MSM).
  • Evidence suggests a shift towards permucosal transmission routes in this population.

Purpose of the Study:

  • To review the epidemiology of HCV infection in HIV-infected MSM.
  • To outline current and future treatment strategies for HCV in this cohort.

Main Methods:

  • Literature review focusing on studies published since 2000.
  • Analysis of epidemiological data on HCV incidence and transmission routes.
  • Examination of risk factors, including behavioral and biological aspects.

Main Results:

  • A rising incidence of acute HCV infection has been observed in HIV-infected MSM globally since 2000.
  • Permucosal transmission, involving sexual practices and mucosally administered drugs, is increasingly implicated.
  • HIV and other sexually transmitted infections are identified as biological risk factors.

Conclusions:

  • Enhanced understanding of HCV epidemiology in HIV-infected MSM is crucial.
  • Effective public health interventions are needed to curb onward HCV transmission.
  • Novel antiviral therapies offer promising treatment avenues.

More Related Videos

A Protocol for Analyzing Hepatitis C Virus Replication13:04

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...